Dengue outbreaks are currently occurring in several countries, notably on the Indian sub-continent. Bangladesh is facing the worst outbreak of dengue since its first recorded epidemic in 2000.

The South Asian nation has seen the number of cases rise to over 92,000 since January 2019, with daily admissions peaking at more than 1,500 new dengue patients in hospitals in recent weeks and is one of the countries to express interest in the Sterile Insect Technique.

Diseases transmitted by mosquitoes such as malaria, dengue, Zika, chikungunya, and yellow fever account for about 17% of all infectious diseases globally, claiming more than 700,000 lives each year, and inflicting suffering on many more. The 2015 outbreak of Zika in Brazil was linked to an increase in the number of babies being born with microcephaly.

New technique proved successful against insects that attack crops and livestock
The Sterile Insect Technique was first developed by the U.S. Department of Agriculture and has been used successfully to target insect pests that attack crops and livestock, such as the Mediterranean fruit fly and the New World screwworm fly.

It is currently in use globally in the agriculture sector on six continents.

The guidance on using the technique to control diseases in humans recommends adopting a phased approach that allows time to test the efficacy of the sterilized insects.

Epidemiological indicators monitor the impact of the method on disease-transmission. It also provides recommendations on mass production of the sterile mosquitoes, government and community engagement, measuring the impact of the technique, and assessing cost-effectiveness.

“Countries seriously affected by dengue and Zika have shown real interest in testing this technology as it can help suppress mosquitoes that are developing resistance to insecticides, which are also negatively impacting the environment,” said Florence Fouque, a scientist at TDR.

The collaborative effort includes plans to support three multi-country teams of research institutions, vector control agencies and public health stakeholders to test the Sterile Insect Technique against Aedes mosquitoes.

 “The use of the Sterile Insect Technique in the agriculture sector in the past 60 years has shown that it is a safe and effective method,” said Jérémy Bouyer, medical entomologist at the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture. “We are excited to collaborate with TDR and WHO to bring this technology to the health sector to fight human diseases.”